Jackson County is a tourism destination for people who enjoy its great outdoors including the Shawnee Ntional Forest and Southern Illinois Wine Trail. The Southernmost Illinois Tourism Bureau serves Jackson County.

Carbondale is home to Southern Illinois University and attracts people attending events at the university and those who enjoy the entertainment, arts, culture and history found in a college town.The Carbondale Tourism serves the Greater Carbondale area.

Murphysboro is the "Barbeque Capital of Illinois" and is home to the Apple Festival, Murphysboro Barbeque Cook-Off, Murphysboro Brew Fest, and the John A. Logan Museum. The Murphysboro Tourism Commission is a commission of the City of Murphysboro and works to promote community events and to promote tourism in Murphysboro.